Three cases of IL36RN-associated pustulosis: An evolution of acrodermatitis continua of Hallopeau to generalized pustular psoriasis

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Two cases of acrodermatitis continua of Hallopeau associated with generalized arthritis.

Acrodermatitis continua of Hallopeau (ACH), a variant of pustular psoriasis, chiefly affects distal parts of the hands and feet (1,2). Arthritis occasionally occurs in psoriasis, including pustular psoriasis, as psoriatic arthritis (3), but it is uncommon in ACH. Here, we report on two cases of ACH with arthritis that was improved by infliximab together with methotrexate as well as salazosulfap...

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OR6-006 – IL36RN alleles in skin auto-inflammation

Results We found IL36RN recessive mutations in patients with GPP (7/84) and localised pustular psoriasis (2/9 cases of Acrodermatitis Continua of Hallopeau and 3/139 cases of plamar-plantar pustulosis), but not among PV cases. Of note, we also identified several affected individuals who carried a single heterozygous mutation. In fact, we uncovered a significant enrichment of heterozygous IL36RN...

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A Case of Acrodermatitis Continua of Hallopeau Following Chronic Pustular Cheilitis

We describe the case of a young male affected by chronic pustular psoriasis of the lips that remained the only manifestation of acrodermatitis continua of Hallopeau (ACH) for years before the onset of the characteristic hand lesions.

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A recalcitrant acrodermatitis continua of Hallopeau successfully treated with etanercept.

Acrodermatitis continua of Hallopeau (ACH) is considered as a localized form of pustularpsoriasis that is usually refractory to the treatment. The condition is characterized by sterile pustules, onychodystrophy, anonychia, and osteolysis of distal phalanges. The authors report a case of recalcitrant ACH who previously failed to topical corticosteroid, methotrexate, acitretin, and phototherapy a...

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Acrodermatitis continua of Hallopeau in a patient with myelodysplastic syndrome.

Acrodermatitis continua of Hallopeau (ACH) is a rare manifestation of pustular psoriasis which may considerably disable affected patients. In this case report we confirm the efficacy of acitretin in the treatment of ACH and, in addition, describe the course of the myelodysplastic syndrome (MDS) from which the patient was suffering. During acitretin treatment, there was a transformation into acu...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology, Venereology and Leprology

سال: 2020

ISSN: 0378-6323

DOI: 10.4103/ijdvl.ijdvl_581_19